* Faun
* Madonna of the Steps (Madonna of the Stairs) (c. 1491) — Marble, 55,5 × 40 cm, Casa Buonarroti, Florence
* Battle of the Centaurs (c. 1492) — Marble, 84,5 × 90,5 cm, Casa Buonarroti, Florence
* Crucifix (1492) — Polychrome wood, 142 × 135 cm, Santo Spirito, Florence
* Hercules
* The Ark of St Dominic San Domenico, Bologna
o St. Petronius (1494–1495) — Marble, height 64 cm
o St. Proclus (1494–1495) — Marble, height 58,5 cm
o Angel (1494–1495) — Marble, height 51,5 cm
* Cupid (Florence)
* Cupid (Rome)
* Bacchus (1496–1497) — Marble, height 203 cm, Museo Nazionale del Bargello, Florence
* Pietà (1499–1500) Marble, height 174 cm, width at the base 195 cm, St. Peter's Basilica, Rome
* Madonna and Child (Madonna of Bruges) (1501–1504) — Marble, height 128 cm, Church of Our Lady, Bruges
* St. Paul (1503–1504) Marble, Cathedral, Siena
* St. Peter (1503–1504) Marble, Cathedral, Siena
* Pius (1503–1504) Marble, Cathedral, Siena
* Madonna and Child with the Infant St. John (Taddei Tondo) (c. 1503) — Marbel, diameter 82,5 cm, Royal Academy of Arts, London
* Madonna and Child (Tondo Pitti) (c. 1503) — 85,8 × 82 cm, Museo Nazionale del Bargello, Florence
* St. Matthew (c. 1505) — Marble, height 271 cm, Galleria dell'Accademia, Florence
* Tomb of Pope Julius II (Underwent six different phases, in 1505, 1513, 1516, 1525–1526, 1532 and 1542)
o Moses (c. 1513–1515) — San Pietro in Vincoli, Rome
o Rebellious Slave (1513–1516) — Louvre, Paris
o Dying Slave (1513–1516) — Louvre, Paris
o The Genius of Victory (c. 1532–1534) — Marble, height 261 cm, Palazzo Vecchio, Florence
o Young Slave,Bearded Slave,Atlas Slave,Awakening Slave, (1513;1519-1535)— Accademia, Florence
o Rachael (1545)
o Leah(1545)
* Medici Chapel (1520–1534) Basilica of San Lorenzo, Florence
o Tomb of Giuliano de' Medici, Night and Day
o Tomb of Lorenzo de' Medici, Evening and Morning (also known as Dusk and Dawn)
o Virgin and Child
* David (1501-1504)
* Apollo (David) (c. 1530) — Marble, height 146 cm, Museo Nazionale del Bargello
* Crouching Boy (c. 1530-1534) — Marble, State Hermitage, St. Petersburg
* Cristo della Minerva (Christ Carrying the Cross) (1519–1520) — Marble, height 205 cm, church of Santa Maria sopra Minerva, Rome
* Brutus (1540) — Marble, height 95 cm, Museo Nazionale del Bargello, Florence
* Florentine Pietà (c. 1550) — Marble, height 253 cm, Museo dell'Opera del Duomo, Florence
* Rondanini Pietà (unfinished, 1552–1564) — Marble, height 195 cm, Castello Sforzesco, Milan